Volume 36
Main Index

Issue 01

Cyclopentadienyl−Carboranyl Hybrid Compounds:  A New Class of Versatile Ligands for Organometallic Chemistry Zuowei Xie pp 1–9 DOI: 10.1021/ar010146i

α-Imino Esters:  Versatile Substrates for the Catalytic, Asymmetric Synthesis of α- and β-Amino Acids and β-Lactams Andrew E. Taggi, Ahmed M. Hafez, and Thomas Lectka pp 10–19 DOI: 10.1021/ar020137p

High-Performance Nanocatalysts for Single-Step Hydrogenations John Meurig Thomas, Brian F. G. Johnson, Robert Raja, Gopinathan Sankar, and Paul A. Midgley pp 20–30 DOI: 10.1021/ar990017q

“Back to the Future”−An Account Discovery of Stable Quasicrystals An-Pang Tsai pp 31–38 DOI: 10.1021/ar010013x

Supramolecular Systems as Microreactors:  Control of Product Selectivity in Organic Phototransformation Chen-Ho Tung, Li-Zhu Wu, Li-Ping Zhang, and Bin Chen pp 39–47 DOI: 10.1021/ar010141l

Transition Metal-Catalyzed Enantioselective Ring-Opening Reactions of Oxabicyclic Alkenes Mark Lautens, Keith Fagnou, and Sheldon Hiebert pp 48–58 DOI: 10.1021/ar010112a

Lepadiformine:  A Case Study of the Value of Total Synthesis in Natural Product Structure Elucidation Steven M. Weinreb pp 59–65 DOI: 10.1021/ar0200403

π-Nucleophilicity in Carbon−Carbon Bond-Forming Reactions Herbert Mayr, Bernhard Kempf, and Armin R. Ofial pp 66–77 DOI: 10.1021/ar020094c

[60]Fullerene−Metal Cluster Complexes:  Novel Bonding Modes and Electronic Communication Kwangyeol Lee, Hyunjoon Song, and Joon T. Park pp 78–86 DOI: 10.1021/ar020149a

Issue 02

Solvation Dynamics and Proton Transfer in Supramolecular Assemblies Kankan Bhattacharyya pp 95–101 DOI: 10.1021/ar020067m

End-Grafted PolysilaneAn Approach to Single Polymer Science Kazuaki Furukawa pp 102–110 DOI: 10.1021/ar020072q

“Design” in Solid-State Chemistry Based on Phase Homologies. The Concept of Structural Evolution and the New Megaseries Am[M1+lSe2+l]2m[M2l+nSe2+3l+n] Antje Mrotzek and Mercouri G. Kanatzidis pp 111–119 DOI: 10.1021/ar020099+

Chlorine Kinetic Isotope Effects on Enzymatic Dehalogenations Piotr Paneth pp 120–126 DOI: 10.1021/ar010101h

Paraherquamides, Brevianamides, and Asperparalines:  Laboratory Synthesis and Biosynthesis. An Interim Report Robert M. Williams and Rhona J. Cox pp 127–139 DOI: 10.1021/ar020229e

Isotope Effects in C−H Bond Activation Reactions by Transition Metals William D. Jones pp 140–146 DOI: 10.1021/ar020148i

Nonoctahedral Structures Konrad Seppelt pp 147–153 DOI: 10.1021/ar020052o

Issue 03

Structural Genomics Ivano Bertini pp 155–155 DOI: 10.1021/ar030023t

Facilities and Methods for the High-Throughput Crystal Structural Analysis of Human Proteins Udo Heinemann, Konrad Büssow, Uwe Mueller, and Patrick Umbach pp 157–163 DOI: 10.1021/ar010129t

Medium-Scale Structural Genomics:  Strategies for Protein Expression and Crystallization Renaud Vincentelli, Christophe Bignon, Arnaud Gruez, Stephane Canaan, Gerlind Sulzenbacher, Mariella Tegoni, Valérie Campanacci, and Christian Cambillau pp 165–172 DOI: 10.1021/ar010130s

High-Throughput Crystallography at an Affordable Cost:  The TB Structural Genomics Consortium Crystallization Facility Bernhard Rupp pp 173–181 DOI: 10.1021/ar020021t

Structural Proteomics:  Toward High-Throughput Structural Biology as a Tool in Functional Genomics Adelinda Yee, Keith Pardee, Dinesh Christendat, Alexei Savchenko, Aled M. Edwards, and Cheryl H. Arrowsmith pp 183–189 DOI: 10.1021/ar010126g

The Southeast Collaboratory for Structural Genomics:  A High-Throughput Gene to Structure Factory Michael W. W. Adams, Harry A. Dailey, Lawrence J. DeLucas, Ming Luo, James H. Prestegard, John P. Rose, and Bi-Cheng Wang, pp 191–198 DOI: 10.1021/ar0101382

Structural Genomics of Membrane Proteins Yoshimasa Kyogoku, Yoshinori Fujiyoshi, Ichio Shimada, Haruki Nakamura, Tomitake Tsukihara, Hideo Akutsu, Takayuki Odahara, Tetsuji Okada, and Nobuo Nomura pp 199–206 DOI: 10.1021/ar0101279

NMR and Structural Genomics David Staunton, Jo Owen, and Iain D. Campbell pp 207–214 DOI: 10.1021/ar010119s

Structural Genomics of Proteins Involved in Copper Homeostasis Lucia Banci and Antonio Rosato pp 215–221 DOI: 10.1021/ar010120r

Issue 04

Thermal Activation of Hydrocarbon C−H Bonds by Cp*M(NO) Complexes of Molybdenum and Tungsten Craig B. Pamplin and Peter Legzdins pp 223–233 DOI: 10.1021/ar0202215

Palladium-Catalyzed α-Arylation of Carbonyl Compounds and Nitriles Darcy A. Culkin and John F. Hartwig pp 234–245 DOI: 10.1021/ar0201106

Peptido- and Glycocalixarenes:  Playing with Hydrogen Bonds around Hydrophobic Cavities Alessandro Casnati, Francesco Sansone, and Rocco Ungaro pp 246–254 DOI: 10.1021/ar0200798

Bond Dissociation Energies of Organic Molecules Stephen J. Blanksby and G. Barney Ellison pp 255–263 DOI: 10.1021/ar020230d

Synthetic Aspects of Stereoselective Hydroformylation Bernhard Breit pp 264–275 DOI: 10.1021/ar0200596

Wavelet:  A New Trend in Chemistry Xue-Guang Shao, Alexander Kai-Man Leung, and Foo-Tim Chau pp 276–283 DOI: 10.1021/ar990163w

Cationic Cyclopentannelation of Allene Ethers Marcus A. Tius pp 284–290 DOI: 10.1021/ar0200394

Issue 05

Electron Transmission through Organized Organic Thin Films R. Naaman and Zeev Vager pp 291–299 DOI: 10.1021/ar010008t

Tyrosinase Autoactivation and the Chemistry of ortho-Quinone Amines Edward J. Land, Christopher A. Ramsden, and Patrick A. Riley pp 300–308 DOI: 10.1021/ar020062p

Assembly of Cytochrome c Oxidase within the Mitochondrion Heather S. Carr and Dennis R. Winge pp 309–316 DOI: 10.1021/ar0200807

The Mechanism of Methanol to Hydrocarbon Catalysis James F. Haw, Weiguo Song, David M. Marcus, and John B. Nicholas pp 317–326 DOI: 10.1021/ar020006o

Microwave Spectroscopy and Nuclear Magnetic Resonance SpectroscopyWhat Is the Connection? David L. Bryce and Roderick E. Wasylishen pp 327–334 DOI: 10.1021/ar020271+

Chemical Approaches to Triggerable Lipid Vesicles for Drug and Gene Delivery Xin Guo and Francis C. Szoka Jr. pp 335–341 DOI: 10.1021/ar9703241

The Building Block Approach to Unusual α-Amino Acid Derivatives and Peptides Sambasivarao Kotha pp 342–351 DOI: 10.1021/ar020147q

Issue 06

Chemical Biology of Signal Transduction pp 353–354 DOI: 10.1021/ar0300672

Applications of One-Bead One-Compound Combinatorial Libraries and Chemical Microarrays in Signal Transduction Research Kit S. Lam, Ruiwu Liu, Suzanne Miyamoto, Alan L. Lehman, and Joseph M. Tuscano pp 370–377 DOI: 10.1021/ar0201299

The Raison D'Être of Constitutively Active Protein Kinases:  The Lesson of CK2 Lorenzo A. Pinna pp 378–384 DOI: 10.1021/ar020164f

Chemical and Mechanistic Approaches to the Study of Protein Tyrosine Phosphatases Zhong-Yin Zhang pp 385–392 DOI: 10.1021/ar020122r

Determinants of Substrate Recognition in Nonreceptor Tyrosine Kinases W. Todd Miller pp 393–400 DOI: 10.1021/ar020116v

Chemical Probes of Signal-Transducing Proteins David S. Lawrence pp 401–409 DOI: 10.1021/ar020132s

Specificity Is Complex and Time Consuming:  Mutual Exclusivity in Tyrosine Kinase-Mediated Signaling Lisa O'Rourke and John E. Ladbury pp 410–416 DOI: 10.1021/ar020167s

Roscovitine and Other Purines as Kinase Inhibitors. From Starfish Oocytes to Clinical Trials Laurent Meijer and Eric Raymond pp 417–425 DOI: 10.1021/ar0201198

Phosphotyrosyl Mimetics in the Development of Signal Transduction Inhibitors Terrence R. Burke, Jr.* and Kyeong Lee pp 426–433 DOI: 10.1021/ar020127o

Synthetic Diacylglycerols (DAG) and DAG-Lactones as Activators of Protein Kinase C (PK-C) Victor E. Marquez and Peter M. Blumberg pp 434–443 DOI: 10.1021/ar020124b

Chemical Approaches to Reversible Protein Phosphorylation Philip A. Cole, Aliya D. Courtney, Kui Shen, Zhongsen Zhang, Yingfeng Qiao, Wei Lu, and Daniel M. Williams pp 444–452 DOI: 10.1021/ar0201254

The Characterization of Protein Post-Translational Modifications by Mass Spectrometry Rebecca E. Schweppe, Claire E. Haydon, Timothy S. Lewis, Katheryn A. Resing, and Natalie G. Ahn pp 453–461 DOI: 10.1021/ar020143l

Protein Kinase Inhibitors as a Therapeutic Modality Alexander Levitzki pp 462–469 DOI: 10.1021/ar0201207

Issue 07

Real-Time Observation of Surface Reactivity and Mobility with Scanning Tunneling Microscopy Xing-Cai Guo and Robert J. Madix pp 471–480 DOI: 10.1021/ar960308o

Rich Structure Chemistry in the Aluminophosphate Family Jihong Yu and Ruren Xu pp 481–490 DOI: 10.1021/ar0201557

Engineering Carbene Rearrangements in Crystals:  From Molecular Information to Solid-State Reactivity Miguel A. Garcia-Garibay pp 491–498 DOI: 10.1021/ar970309w

Lanthanide−Transition-Metal Complexes:  From Ion Pairs to Extended Arrays Christine E. Plečnik, Shengming Liu, and Sheldon G. Shore pp 499–508 DOI: 10.1021/ar010050o

Asymmetric Photoreactions within Zeolites:  Role of Confinement and Alkali Metal Ions J. Sivaguru, Arunkumar Natarajan, Lakshmi S. Kaanumalle, J. Shailaja, Sundararajan Uppili, Abraham Joy, and V. Ramamurthy pp 509–521 DOI: 10.1021/ar020269i

ENDOR of Metalloenzymes Brian M. Hoffman pp 522–529 DOI: 10.1021/ar0202565

Organization of Signaling Complexes by PDZ-Domain Scaffold Proteins Mingjie Zhang and Wenning Wang pp 530–538 DOI: 10.1021/ar020210b

Enzymes with Molecular Tunnels Frank M. Raushel, James B. Thoden, and Hazel M. Holden pp 539–548 DOI: 10.1021/ar020047k

Nanoparticles:  Scaffolds and Building Blocks Roy Shenhar and Vincent M. Rotello pp 549–561 DOI: 10.1021/ar020083j

Synthetic Artificial Peptidases and Nucleases Using Macromolecular Catalytic Systems Junghun Suh pp 562–570 DOI: 10.1021/ar020037j

Issue 08

Viscosity as an Experimental Tool in Studying the Mechanism of Stereoselective and Product-Selective Chemical Transformations through Frictional Impositions Waldemar Adam and Alexei V. Trofimov pp 571–579 DOI: 10.1021/ar020260g

Unequivocal SRN1 Route of Vinyl Halides with a Multitude of Competing Pathways:  Reactivity and Structure of the Vinyl Radical Intermediate Carlo Galli and Zvi Rappoport pp 580–587 DOI: 10.1021/ar030028q

Enzymatic Transition State Poise and Transition State Analogues Vern L. Schramm pp 588–596 DOI: 10.1021/ar0200495

Controlling Flows in Microchannels with Patterned Surface Charge and Topography Abraham D. Stroock and George M. Whitesides pp 597–604 DOI: 10.1021/ar0202870

Orientational Dynamics of Liquids Confined in Nanoporous Sol−Gel Glasses Studied by Optical Kerr Effect Spectroscopy Richard A. Farrer and John T. Fourkas pp 605–612 DOI: 10.1021/ar0200302

Humanization of Lepidopteran Insect-Cell-Produced Glycoproteins Noboru Tomiya, Michael J. Betenbaugh, and Yuan C. Lee pp 613–620 DOI: 10.1021/ar020202v

Cucurbituril Homologues and Derivatives:  New Opportunities in Supramolecular Chemistry Jae Wook Lee, S. Samal, N. Selvapalam, Hee-Joon Kim, and Kimoon Kim pp 621–630 DOI: 10.1021/ar020254k

Physicochemical Aspects of Host−Guest Compounds Luigi R. Nassimbeni pp 631–637 DOI: 10.1021/ar0201153

Formation of Carbon−Carbon Bonds under Catalysis by Transition-Metal Nanoparticles Marcial Moreno-Mañas and Roser Pleixats pp 638–643 DOI: 10.1021/ar020267y

Issue 09

[3+2] versus [2+2] Addition of Metal Oxides Across CC Bonds. Reconciliation of Experiment and Theory Dirk V. Deubel and Gernot Frenking pp 645–651 DOI: 10.1021/ar020268q

Perspectives on the Formation of Polychlorinated Dibenzo-p-dioxins and Dibenzofurans during Municipal Solid Waste (MSW) Incineration and Other Combustion Processes Kari Tuppurainen, Arja Asikainen, Päivi Ruokojärvi, and Juhani Ruuskanen pp 652–658 DOI: 10.1021/ar020104+

Asymmetric Catalysis with Chiral Ferrocene Ligands Li-Xin Dai, Tao Tu, Shu-Li You, Wei-Ping Deng, and Xue-Long Hou pp 659–667 DOI: 10.1021/ar020153m

Reversible Binding of Oxygen to Aromatic Compounds Jean-Marie Aubry, Christel Pierlot, Jean Rigaudy, and Reinhard Schmidt pp 668–675 DOI: 10.1021/ar010086g

Core-Modified Expanded Porphyrins:  New Generation Organic Materials Tavarekere K. Chandrashekar and Sundararaman Venkatraman pp 676–691 DOI: 10.1021/ar020284n

Optically Switchable Molecular Solids:  Photoinduced Spin-Crossover, Photochromism, and Photoinduced Magnetization Osamu Sato pp 692–700 DOI: 10.1021/ar020242z

Transition Metal-Catalyzed/Mediated Reaction of Allenes with a Nucleophilic Functionality Connected to the α-Carbon Atom Shengming Ma pp 701–712 DOI: 10.1021/ar020133k

Cholesterol Oxidases:  A Study of Nature's Approach to Protein Design Nicole S. Sampson and Alice Vrielink pp 713–722 DOI: 10.1021/ar9800587

Issue 10

Close Encounters of the Transient Kind:  Protein Interactions in the Photosynthetic Redox Chain Investigated by NMR Spectroscopy Peter B. Crowley and Marcellus Ubbink pp 723–730 DOI: 10.1021/ar0200955

Palladium-Catalyzed Coupling of sp2-Hybridized Tellurides Gilson Zeni, Antonio L. Braga, and Hélio A. Stefani pp 731–738 DOI: 10.1021/ar0202621

Titanium-Catalyzed Enantioselective Additions of Alkyl Groups to Aldehydes:  Mechanistic Studies and New Concepts in Asymmetric Catalysis Patrick J. Walsh pp 739–749 DOI: 10.1021/ar0300219

A Conversation on VB vs MO Theory:  A Never-Ending Rivalry? Roald Hoffmann, Sason Shaik, Philippe C. Hiberty pp 750–756 DOI: 10.1021/ar030162a

Avoiding the Road Less Traveled:  How the Topology of Enzyme−Substrate Complexes Can Dictate Product Selection Andrew C. Eliot and Jack F. Kirsch pp 757–765 DOI: 10.1021/ar0202767

Stereoselective Synthesis of Polypropionate Units and Heterocyclic Compounds by Cyclopropylcarbinol Ring-Opening with Mercury(II) Salts Christophe Meyer, Nicolas Blanchard, Magali Defosseux, and Janine Cossy pp 766–772 DOI: 10.1021/ar020154e

The Emergence of Allenamides in Organic Synthesis Lin-li Wei, Hui Xiong, and Richard P. Hsung pp 773–782 DOI: 10.1021/ar030029i

PARACEST Agents:  Modulating MRI Contrast via Water Proton Exchange Shanrong Zhang, Matthew Merritt, Donald E. Woessner, Robert E. Lenkinski, and A. Dean Sherry pp 783–790 DOI: 10.1021/ar020228m

Multiple Transient Response Methods To Identify Mechanisms of Heterogeneous Catalytic Reactions Yun Hang Hu and Eli Ruckenstein pp 791–797 DOI: 10.1021/ar0300367

Electron Transfer between Membrane Complexes and Soluble Proteins in Photosynthesis Manuel Hervás, José A. Navarro, and Miguel A. De la Rosa pp 798–805 DOI: 10.1021/ar020084b

Issue 11

Functionalized Fullerenes in Water. The First 10 Years of Their Chemistry, Biology, and Nanoscience Eiichi Nakamura and Hiroyuki Isobe pp 807–815 DOI: 10.1021/ar030027y

Analogies between Boron and Carbon Eluvathingal D. Jemmis and Elambalassery G. Jayasree pp 816–824 DOI: 10.1021/ar0300266

Biochemical and Biophysical Properties of the CO-Sensing Transcriptional Activator CooA Shigetoshi Aono pp 825–831 DOI: 10.1021/ar020097p

Hydrogen-Bonding-Induced Phenomena in Bifunctional Heteroazaaromatics Jacek Waluk pp 832–838 DOI: 10.1021/ar0200549

New Approaches to the Deduction of Complex Reaction Mechanisms John Ross pp 839–847 DOI: 10.1021/ar020285f

Gas Phase Studies of the Competition between Substitution and Elimination Reactions Scott Gronert pp 848–857 DOI: 10.1021/ar020042n

High-Resolution Solid-State NMR Applied to Polypeptides and Membrane Proteins Sorin Luca, Henrike Heise, and Marc Baldus pp 858–865 DOI: 10.1021/ar020232y

Issue 12

Scientific Basis for Process and Catalyst Design in the Selective Oxidation of Methane to Formaldehyde Francesco Arena and Adolfo Parmaliana pp 867–875 DOI: 10.1021/ar020064+

Femtosecond Absorption Spectroscopy of Transition Metal Charge-Transfer Complexes James K. McCusker pp 876–887 DOI: 10.1021/ar030111d

Chromophore-Functionalized Gold Nanoparticles K. George Thomas and Prashant V. Kamat pp 888–898 DOI: 10.1021/ar030030h

Strategies for Heterocyclic Construction via Novel Multicomponent Reactions Based on Isocyanides and Nucleophilic Carbenes Vijay Nair, C. Rajesh, A. U. Vinod, S. Bindu, A. R. Sreekanth, J. S. Mathen, and Lakshmi Balagopal pp 899–907 DOI: 10.1021/ar020258p

Asymmetric Catalytic Hydrogenation. Design of New Ru Catalysts and Chiral Ligands:  From Laboratory to Industrial Applications Jean-Pierre Genet pp 908–918 DOI: 10.1021/ar020152u

Molecular Tweezers and Clips as Synthetic Receptors. Molecular Recognition and Dynamics in Receptor−Substrate Complexes Frank-Gerrit Klärner and Björn Kahlert pp 919–932 DOI: 10.1021/ar0200448

Ligand-Bridged Oligomeric and Supramolecular Arrays of the Hexanuclear Rhenium Selenide Clusters−Exploratory Synthesis, Structural Characterization, and Property Investigation Hugh D. Selby, Bryan K. Roland, and Zhiping Zheng pp 933–944 DOI: 10.1021/ar020134c

Substrate-Mediated Interactions and Intermolecular Forces between Molecules Adsorbed on Surfaces E. Charles H. Sykes, Patrick Han, S. Alex Kandel, Kevin F. Kelly, Gregory S. McCarty, and Paul S. Weiss pp 945–953 DOI: 10.1021/ar970286l